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However, in M.tb -infected immunocompromised mice, JHU083 showed reduced therapeutic efficacy [36]

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Tissue concentrations of nitrite, superoxide dismutase (SOD), and malondialdehyde (MDA), as markers of oxidative stress, were enhanced by both conventional and NP formulations

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Among the diverse array of contaminants, organic pollutantssuch as industrial dyes, pharmaceutical waste, contaminants of emerging concern (CECs), and harmful biological agentspose severe risks to ecosystems and human health 11,25